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Ebastine Impurity 1

SZ CAT No SZ-E019011
CAS No 1661001-35-9
Mol.F. C32H39NO2
Mol.Wt. 469.7
Inv. Status Under Synthesis

Chemical Name: (1R,2R)-2-(4-(Benzhydryloxy)piperidin-1-yl)-1-(4-(tert-butyl)phenyl)-2-methylcyclopropan-1-ol

Smiles: O[C@]1(C2=CC=C(C(C)(C)C)C=C2)[C@](C)(N3CCC(OC(C4=CC=CC=C4)C5=CC=CC=C5)CC3)C1

Inchi: InChI=1S/C32H39NO3/c1-32(2,24-34)28-17-15-25(16-18-28)30(35)14-9-21-33-22-19-29(20-23-33)36-31(26-10-5-3-6-11-26)27-12-7-4-8-13-27/h3-8,10-13,15-18,29,31,34H,9,14,19-24H2,1-2H3

Green HPTLC-densitometric approach for simultaneous determination and impurity- profiling of ebastine and phenylephrine hydrochloride
Amal M. Abou Al-Alamein, Mohamed K. Abd El-Rahman, Ezzat M. Abdel-Moety, Esraa M. Fawaz
Microchemical Journal Volume 147, June 2019, Pages 1097-1102
Using an innovative Quality-by-Design approach for development of a stability indicating UHPLC method for ebastine in the API and pharmaceutical formulations
Alexander H. Schmidt a,∗, Imre Molnár
Journal of Pharmaceutical and Biomedical Analysis 78–79 (2013) 65–74
Development and Validation of a Stability-Indicating Liquid Chromatographic Method for Estimating Olmesartan Medoxomil Using Quality by Design
Sarwar Beg, Gajanand Sharma, O.P. Katare, Shikha Lohan, Bhupinder Singh
Journal of Chromatographic Science, Volume 53, Issue 7, August 2015, Pages 1048–1059