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Citalopram EP Impurity C

SZ CAT No SZ-C039005
CAS No 372941-54-3
Mol.F. C20H19FN2O2
Mol.Wt. 338.4
Inv. Status In Stock
Rel. CAS No 1440961-11-4 (Oxalate salt) 
Rel. CAT No SZ-E002004,


SynZeal product information given on this website is as per the existing understanding while publishing the details on website. The customer is responsible for assessing the accuracy of the information at the time of actual purchase.

SynZeal will update these details as per new development or finding in product specification without further noticed.

Chemical Name: (3RS)-6-Cyano-3-[3-(dimethylamino)propyl]-3-(4-fluorophenyl)isobenzofuran-1(3H)-one (as per EP) ; 3-(3-Dimethylaminopropyl)-3-(4-fluorophenyl)-6-cyano-1(3H)-isobenzofuranone (as per USP)

Synonym: Citalopram USP Related Compound C

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O=C1OC(CCCN(C)C)(C2=CC=C(F)C=C2)C3=C1C=C(C#N)C=C3

Citalopram EP Impurity C is chemically (3RS)-6-Cyano-3-[3-(dimethylamino)propyl]-3-(4-fluorophenyl)isobenzofuran-1(3H)-one (as per EP) ; 3-(3-Dimethylaminopropyl)-3-(4-fluorophenyl)-6-cyano-1(3H)-isobenzofuranone (as per USP). It is also known as Citalopram USP Related Compound C. Citalopram EP Impurity C is supplied with detailed characterization data compliant with regulatory guideline. Citalopram EP Impurity C can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Citalopram.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Semi-preparative isolation and structural elucidation of an impurity in citalopram by LC/MS/MS
Bhanu Ramana,∗, Brajesh A. Sharmaa,b, Pradeep D. Ghugare b, Pravin P. Karmuse b, Ashok Kumar b
Journal of Pharmaceutical and Biomedical Analysis 50 (2009) 377–383
Isolation and characterization of degradation products of citalopram and process-related impurities using RP-HPLC
Ramisetti Nageswara Rao Ale Narasa Raju Ramaram Narsimha
J. Sep. Sci. 2008, 31, 1729 – 1738
Improved One-Pot Synthesis of Citalopram Diol and Its Conversion to Citalopram
Ravindra Vedantham, VNKV Prasada Raju Vetukuri, Ambaiah Boini, Mukkanti Khagga, and Rakeshwar Bandichhor
Org. Process Res. Dev. 2013, 17, 5, 798–805
Characterization of an unknown impurity in citalopram hydrobromide active pharmaceutical ingredient by semi-preparative isolation and lc-esi/msn and nmr
Saji Thomas,1 Ashutosh Agarwal,1 Raghavendra Desai Rao,2 and Chandra S. Mathela
Journal of Liquid Chromatography & Related Technologies, 36:1999–2012, 2013

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