Chemical Name: (3RS)-3-(3,4-Dichlorophenyl)-3hydroxy-2,3-dihydro-1H-isoindol-1-one ;
Synonym: Chlorthalidone Dichloro Impurity
Smiles: O=C1N[C@@](O)(C2=CC=C(Cl)C(Cl)=C2)C3=C1C=CC=C3
Inchi: InChI=1/C28H19Cl2N3O8S2/c29-21-11-9-15(27(36)19-7-3-1-5-17(19)25(34)31-27)13-23(21)42(38,39)33-43(40,41)24-14-16(10-12-22(24)30)28(37)20-8-4-2-6-18(20)26(35)32-28/h1-14,33,36-37H,(H,31,34)(H,32,35)
Investigation of novel supersaturating drug delivery systems of chlorthalidone: The use of polymer-surfactant complex as an effective carrier in solid dispersions
Maria TerezinhaFrançaRafaelNicolay PereiraManoelaKlüppel RiekesJulianaMunari Oliveira PintoHellen KarineStulzer
European Journal of Pharmaceutical Sciences Volume 111, 1 January 2018, Pages 142-152
A Validated RP-HPLC Stability Method for the Estimation of Chlorthalidone and Its Process-Related Impurities in an API and Tablet Formulation
Chaitali Kharat,1 Vaishali A. Shirsat , 1 Yogita M. Kodgule,2 and Mandar Kodgule
Hindawi International Journal of Analytical Chemistry Volume 2020, Article ID 3593805, 11 pages
Stability-Indicating RP-UPLC Method for Simultaneous Determination of Azilsartan Medoxomil and Chlorthalidone in Tablets in the Presence of Its Degradation Products
Lobna A Hussein, Nancy N Magdy, Michael A Ibrahim
Journal of Chromatographic Science, Volume 57, Issue 3, March 2019, Pages 213–219