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Brexpiprazole Impurity 9

SZ CAT No SZ-B011010
CAS No 31570-97-5
Mol.F. C9H7NO2 
Mol.Wt. 161.2
Inv. Status Custom Synthesis


Chemical Name: 5-Hydroxyquinolin-2(1H)-one

Synonym: 2,5-Dihydroxyquinoline

Industry-Oriented Route Evaluation and Process Optimization for the Preparation of Brexpiprazole
Weiming Chen, Jin Suo, Yongjian Liu, Yuanchao Xie, Mingjun Wu, Fuqiang Zhu, Yifeng Nian, Haji Akber Aisa, and Jingshan Shen
Org. Process Res. Dev. 2019, 23, 5, 852–857
 
Development and Validation of Stability Indicating Assay Method and Characterization of Degradation Product for Brexpiprazole Bulk by RP-HPLC
Nehal P Bhatt1*, Ashok B Patel1 , Mohana Rao Sanaka2 , Amit J Vyas1 , Nilesh K Patel1 and Ajay I Patel
Journal of Chemical and Pharmaceutical Research, 2018, 10(1):55-66
 
Qualification of impurities based on metabolite data.
LarsWeidolf,ThomasAndersson,JoelP.Bercu,AndreasBrink,SusanneGlowienke,JamesHarvey,Martin A.Hayes,PascaleJacques,ChuangLu,NenadManevski,WolfgangMuster,RaphaelNudelman,RonOgilvie,JennyOttosson,AndrewTeasdale,BruceTrela
Regulatory Toxicology and Pharmacology Volume 110, February 2020, 104524