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Bosutinib Regio Isomer Impurity

SZ CAT No SZ-B063027
CAS No 1391063-17-4
Mol.F. C26H29Cl2N5O3
Mol.Wt. 530.5
Inv. Status Custom Synthesis


Chemical Name: 4-((3,5-Dichloro-4-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methyl piperazin-1-yl)propoxy)quinoline-3-carbonitrile

Smiles: N#CC1=C(NC2=CC(Cl)=C(OC)C(Cl)=C2)C3=CC(OC)=C(OCCCN4CCN(C)CC4)C=C3N=C1

Inchi: InChI=1S/C27H44O2/c1-19-10-13-23(28)18-22(19)12-11-21-9-7-17-27(5)24(14-15-25(21)27)20(2)8-6-16-26(3,4)29/h9,11-12,20,23-25,28-29H,6-8,10,13-18H2,1-5H3/b12-11-/t20-,23+,24-,25+,27-/m1/s1

Method development and validation for related substances of Bosutinib monohydrate by RP-​HPLC method
By Parmar, Yogendra B.; Shah, Dharmesh; Majmudar, Yashraj A.; Kaka, Ketul C.; Patel, Arpan S.; Kankad, Pankaj D.; Sartanpara, Uday G.
From World Journal of Pharmacy and Pharmaceutical Sciences (2021), 10(1), 838-854
 
RP-​HPLC method for estimation of Bosutinib in bulk form as per ICH guidelines
By Chaudhari, Vidya L.; Kulkarni, Amol A.
From World Journal of Pharmaceutical Research (2016), 5(12), 417-424