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Bosutinib Desmethyl Impurity

SZ CAT No SZ-B063003
CAS No 2468737-92-8
Mol.F. C25H27Cl2N5O3
Mol.Wt. 516.4
Inv. Status Under Synthesis


Chemical Name: 4-((2,4-Dichloro-5-hydroxyphenyl)amino)-6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinoline-3-carbonitrile

Smiles: ClC1=CC(Cl)=C(O)C=C1NC(C2=C3C=C(OCCCN4CCN(C)CC4)C(OC)=C2)=C(C=N3)C#N

Inchi: InChI=1S/C24H25Cl2N5O3/c1-30-4-6-31(7-5-30)3-2-8-34-23-12-19-16(9-22(23)33)24(15(13-27)14-28-19)29-20-11-21(32)18(26)10-17(20)25/h9-12,14,32-33H,2-8H2,1H3,(H,28,29)

Method development and validation for related substances of Bosutinib monohydrate by RP-​HPLC method
By Parmar, Yogendra B.; Shah, Dharmesh; Majmudar, Yashraj A.; Kaka, Ketul C.; Patel, Arpan S.; Kankad, Pankaj D.; Sartanpara, Uday G.
From World Journal of Pharmacy and Pharmaceutical Sciences (2021), 10(1), 838-854
 
RP-​HPLC method for estimation of Bosutinib in bulk form as per ICH guidelines
By Chaudhari, Vidya L.; Kulkarni, Amol A.
From World Journal of Pharmaceutical Research (2016), 5(12), 417-424