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Bosutinib Propoxy Dimer Impurity

SZ CAT No SZ-B063021
CAS No 2095306-27-5
Mol.F. C39H30Cl4N6O6
Mol.Wt. 820.5
Inv. Status Under Synthesis


Chemical Name: 7,7'-(Propane-1,3-diylbis(oxy))bis(4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxyquinoline-3-carbonitrile)

Smiles: ClC1=C(OC)C=C(NC2=C(C#N)C=NC3=CC(OCCCOC4=C(OC)C=C5C(N=CC(C#N)=C5NC6=C(Cl)C=C(Cl)C(OC)=C6)=C4)=C(OC)C=C23)C(Cl)=C1

Inchi: InChI=1S/C15H13I2NO4/c16-11-5-8(7-13(18)15(20)21)6-12(17)14(11)22-10-3-1-9(19)2-4-10/h1-6,13,19H,7,18H2,(H,20,21)/t13-/m0/s1

Method development and validation for related substances of Bosutinib monohydrate by RP-​HPLC method
By Parmar, Yogendra B.; Shah, Dharmesh; Majmudar, Yashraj A.; Kaka, Ketul C.; Patel, Arpan S.; Kankad, Pankaj D.; Sartanpara, Uday G.
From World Journal of Pharmacy and Pharmaceutical Sciences (2021), 10(1), 838-854
 
RP-​HPLC method for estimation of Bosutinib in bulk form as per ICH guidelines
By Chaudhari, Vidya L.; Kulkarni, Amol A.
From World Journal of Pharmaceutical Research (2016), 5(12), 417-424