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Bosutinib Impurity 8

SZ CAT No SZ-B063025
CAS No 380844-49-5
Mol.F. C21H18Cl3N3O3
Mol.Wt. 466.7
Inv. Status Custom Synthesis


Chemical Name: 7-(3-Chloropropoxy)-4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxyquinoline-3-carbonitrile

Smiles: ClC1=CC(Cl)=C(OC)C=C1NC(C2=C3C=C(OCCCCl)C(OC)=C2)=C(C=N3)C#N

Inchi: InChI=1/C21H23NO4.C2HF3O2/c1-22(2)11-5-8-17-16-7-4-3-6-15(16)13-26-19-10-9-14(12-18(17)19)20(23)21(24)25;3-2(4,5)1(6)7/h3-4,6-10,12,20,23H,5,11,13H2,1-2H3,(H,24,25);(H,6,7)/b17-8+;

Method development and validation for related substances of Bosutinib monohydrate by RP-​HPLC method
By Parmar, Yogendra B.; Shah, Dharmesh; Majmudar, Yashraj A.; Kaka, Ketul C.; Patel, Arpan S.; Kankad, Pankaj D.; Sartanpara, Uday G.
From World Journal of Pharmacy and Pharmaceutical Sciences (2021), 10(1), 838-854
 
RP-​HPLC method for estimation of Bosutinib in bulk form as per ICH guidelines
By Chaudhari, Vidya L.; Kulkarni, Amol A.
From World Journal of Pharmaceutical Research (2016), 5(12), 417-424