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Abacavir Nitroso Impurity 1

SZ CAT No SZ-A049027
CAS No NA
Mol.F. C11H13ClN6O3
Mol.Wt. 312.7
Inv. Status Custom Synthesis


Chemical Name: N-(2-Amino-4-chloro-6-(((1S,4R)-4-(hydroxymethyl)cyclopent-2-en-1-yl)(nitroso)amino)pyrimidin-5-yl)formamide

Smiles: NC1=NC(Cl)=C(NC([H])=O)C(N([C@@H]2C=C[C@H](CO)C2)N=O)=N1

Inchi: InChI=1S/C17H25N3O/c18-10-15-2-1-3-20(15)16(21)11-19-17-7-12-4-13(8-17)6-14(5-12)9-17/h12-15,19H,1-9,11H2/t12?,13?,14?,15-,17?/m0/s1

Stability indicating RP-​HPLC method development and validation for determination of abacavir sulphate in tablet dosage form
By Ithape, Aniket B.; Deshpande, Padmanabh B.; Shelke, Priyanka
From International Journal of Pharmacy and Pharmaceutical Research (2020), 17(4), 670-680
 
A new stability indicating method was developed and validated for the simultaneous estimation of Lamivudine and Abacavir in tablet dosage form by RP-​HPLC
By Rajamahanti, Santoshi G.; Annapurna, N.; Santosh, T.; Durga, B.; Raziya, S. K.
From Research Journal of Pharmaceutical, Biological and Chemical Sciences (2017), 8(3), 407-421
 
A validated stability-​indicating RP-​HPLC method for abacavir sulfate in the presence of degradation products, its process-​related impurities and identification of oxidative degradant by LC-​MS​/MS
By Ragham, Pramod Kumar; Chandrasekhar, Kothapalli B.; Reddy, J. Rudraprasad; Kasturi, Krishna Mohan
From Indo American Journal of Pharmaceutical Research (2015), 5(1), 463-473