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Telmisartan N-Desmethyl Impurity

SZ目录编号 SZ-T006012
CAS 号 144701-81-5
分子式 C32H28N4O2
分子量 500.2
投资状态 Out of Stock, Under Synthesis


化学名称: 4'-((7'-methyl-2'-propyl-1H,3'H-[2,5'-bibenzo[d]imidazol]-3'-yl)methyl)-[1,1'-biphenyl]-2-carboxylic acid

微笑: CC1=CC(C2=NC(C=CC=C3)=C3N2)=CC4=C1N=C(CCC)N4CC5=CC=C(C(C=CC=C6)=C6C(O)=O)C=C5

印地语: InChI=1S/C37H38N4O2/c1-7-12-33-38-31-22-27(35-39-30-15-10-11-16-32(30)40(35)6)21-24(2)34(31)41(33)23-25-17-19-26(20-18-25)28-13-8-9-14-29(28)36(42)43-37(3,4)5/h8-11,13-22H,7,12,23H2,1-6H3

Detection, isolation and characterization of principle synthetic route indicative impurity in telmisartan
V.Srinivasan, H.Sivaramakrishnan, B.Karthikeyan
Arabian Journal of Chemistry Volume 9, Supplement 2, November 2016, Pages S1516-S1522
 
Quality-by-design approach for the development of telmisartan potassium tablets
Ga-Hui Oh, Jin-Hyun Park, Hye-Won Shin, Joo-Eun Kim, Young-Joon Park
Drug Dev Ind Pharm. 2018 May;44(5):837-848.
 
An Efficient and Impurity-Free Process for Telmisartan:  An Antihypertensive Drug
Kikkuru Srirami Reddy, Neti Srinivasan, Chinta Raveendra Reddy, Naveenkumar Kolla, Yerremilli Anjaneyulu, Sundaram Venkatraman, Apurba Bhattacharya, and Vijayavitthal T. Mathad
Org. Process Res. Dev. 2007, 11, 1, 81–85
 
Simultaneous determination of Telmisartan impurities and Chlorthalidone impurities by UPLC
B. Marineni, T. Sreenivasulu Reddy
International Journal of Pharmaceutical Sciences Review and Research 26(2):226-230