化学名称: (2S,5R,6R)-6-[(2R)-2-(4-Ethyl-2,3-dioxopiperazine-1-carboxamido)-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid monohydrate (as per EP);(2S,5R,6R)-6-[(R)-2-(4-Ethyl-2,3-dioxo-1-piperazinecarboxamido)-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid monohydrate (as per USP)
微笑: O=C([C@@H](C1=CC=CC=C1)NC(N(CCN(CC)C2=O)C2=O)=O)N[C@H]3[C@](SC(C)(C)[C@@H]4C(O)=O)([H])N4C3=O.O
印地语: InChI=1S/C34H50N6O10S2/c1-13-23(36-24(33(47)48)27(13)51-17-9-19(35-11-17)29(43)37(5)6)21(15(3)41)31(45)39-12-18(10-20(39)30(44)38(7)8)52-28-14(2)25-22(16(4)42)32(46)40(25)26(28)34(49)50/h13-23,25,35-36,41-42H,9-12H2,1-8H3,(H,47,48)(H,49,50)/t13-,14-,15-,16-,17+,18+,19+,20+,21-,22-,23-,25-/m1/s1
Quantification of cefepime, meropenem, piperacillin, and tazobactam in human plasma using a sensitive and robust liquid chromatography-tandem mass spectrometry method, part 2: stability evaluation
By D'cunha, Ronilda; Bach, Thanh; Young, Beth Ann; Li, Peizhi; Nalbant, Demet; Zhang, Jun; Winokur, Patricia; An, Guohua
From Antimicrobial Agents and Chemotherapy (2018), 62(9), e00861-18/1-e00861-18/9
Stability indicating RP-HPLC method for the determination of Piperacillin and Tazobactam and their related substances in bulk and pharmaceutical formulation
By Navle, Khyathi; Prasanna, B. Lakshmi; Dometti, Hema Sree; Moodu, Shankar
From World Journal of Pharmacy and Pharmaceutical Sciences (2017), 6(8), 1760-1774
Therapeutic drug monitoring of beta-lactam antibiotics - Influence of sample stability on the analysis of piperacillin, meropenem, ceftazidime and flucloxacillin by HPLC-UV
By Pinder, Nadine; Brenner, Thorsten; Swoboda, Stefanie; Weigand, Markus A.; Hoppe-Tichy, Torsten
From Journal of Pharmaceutical and Biomedical Analysis (2017), 143, 86-93