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O-Desmethyl Midostaurin (CGP62221)

SZ目录编号 SZ-M063005
CAS 号 740816-86-8
分子式 C34H28N4O4
分子量 556.6
投资状态 In Stock


化学名称: N-((5S,6R,7R,9R)-6-hydroxy-5-methyl-14-oxo-6,7,8,9,15,16-hexahydro-5H,14H-17-oxa-4b,9a,15-triaza-5,9-methanodibenzo[b,h]cyclonona[jkl]cyclopenta[e]-as-indacen-7-yl)-N-methylbenzamide

异名: O-Desmethyl-PKC 412

微笑: C[C@](O[C@@]1([H])N(C2=CC=CC=C32)C4=C3C5=C6CNC5=O)([C@@H]([C@H](N(C)C(C7=CC=CC=C7)=O)C1)O)N8C4=C6C9=CC=CC=C89

印地语: InChI=1S/C24H42N2O4/c1-15(2)7-18-10-21(27)25(13-18)24(20(9-17(5)6)12-23(29)30)26-14-19(8-16(3)4)11-22(26)28/h15-20,24H,7-14H2,1-6H3,(H,29,30)/t18-,19-,20?/m0/s1

Impurity profiling and stability-​indicating method development and validation for the estimation of assay and degradation impurities of midostaurin in softgel capsules using HPLC and LC-​MS
By Lakka, Narasimha Swamy; Kuppan, Chandrasekar; Ravinathan, Poornima
From Biomedical Chromatography (2021), Ahead of Print.

RP-​HPLC method development and validation for the estimation of midostaurin in bulk and pharmaceutical dosage form
By Harikrishnan, Narayanaswamy; Subramanian, Gejalakshmi; Hemalatha, C. N.; Pavankumar, V.
From International Journal of Research in Pharmaceutical Sciences (Madurai, India) (2020), 11(4), 5108-5112

Impurity profiling and stability-​indicating method development and validation for the estimation of assay and degradation impurities of midostaurin in softgel capsules using HPLC and LC-​MS
By Lakka Narasimha Swamy; Kuppan Chandrasekar; Ravinathan Poornima
From Biomedical chromatography : BMC (2021), e5222