化学名称: 2-Cyclohexene-1-carboxylic acid, 2-methyl-6-(3-nitrophenyl)-4-oxo-, methyl ester; Methyl 2-methyl-6-(3-nitrophenyl)-4-oxo-2-cyclohexene-1-carboxylate;
异名: Nicardipine Impurity A
微笑: O=C(C1C(C)=CC(CC1C2=CC=CC([N+]([O-])=O)=C2)=O)OC
印地语: InChI=1S/C7H5NO4/c9-6(10)4-1-5(7(11)12)3-8-2-4/h1-3H,(H,9,10)(H,11,12)
Stability-indicating HPLC method for the determination of nicardipine in capsules and spiked human plasma. Identification of degradation products using HPLC/MS
Sheikha M.Al-Ghannam,Abeer M.Al-Olayan
Arabian Journal of Chemistry Volume 12, Issue 8, December 2019, Pages 1983-1993
Employing ionization behaviors to resolve a trace-level impurity: determination of 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5- pyridinedicarboxylic acid di-2-[methyl-(phenylmethyl)amino]ethyl ester in nicardipine drug substance
M B Maurin 1, R D Vickery, P Ma, J Manalo, M A Hussain
Pharm Res. 1992 Nov;9(11):1518-20.
Chromatographic purity and assay of nicardipine by HPLC
C. V. Fernández D. F. Mira G. I. Luque
Journal of High Resolution Chromatography Volume13, Issue12 December 1990 Pages 846-849
Identification and characterization of a novel potential degradant and development and validation of stability-indicating rp-lc method for nicardipine impurities in injectable dosage form
Bhupendrasinh K. Vaghela &Surendra Singh Rao
Journal of Liquid Chromatography & Related Technologies Volume 36, 2013 - Issue 15 Pages 2166-2181