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Nicardipine Impurity 5

SZ目录编号 SZ-N004020
分子式 C26H28N2O7
分子量 480.5
投资状态 Custom Synthesis

化学名称: 2-(2-(Benzyl(methyl)amino)ethyl) 6-methyl 5-methyl-3'-nitro-3-oxo-1,2,3,6-tetrahydro-[1,1'-biphenyl]-2,6-dicarboxylate

微笑: O=C(C(C(C1=CC=CC([N+]([O-])=O)=C1)C2C(OCCN(CC3=CC=CC=C3)C)=O)C(C)=CC2=O)OC

印地语: InChI=1S/C30H33N7O9S/c38-30(34-47(43,44)24-2-4-26(27(17-24)36(40)41)32-18-20-6-13-45-14-7-20)25-3-1-22(37(42)11-9-35(39)10-12-37)16-28(25)46-23-15-21-5-8-31-29(21)33-19-23/h1-5,8,15-17,19-20,32,35H,6-7,9-14,18H2,(H,31,33)(H,34,38)

Stability-indicating HPLC method for the determination of nicardipine in capsules and spiked human plasma. Identification of degradation products using HPLC/MS
Sheikha M.Al-Ghannam,Abeer M.Al-Olayan
Arabian Journal of Chemistry Volume 12, Issue 8, December 2019, Pages 1983-1993
Employing ionization behaviors to resolve a trace-level impurity: determination of 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5- pyridinedicarboxylic acid di-2-[methyl-(phenylmethyl)amino]ethyl ester in nicardipine drug substance
M B Maurin 1, R D Vickery, P Ma, J Manalo, M A Hussain
Pharm Res. 1992 Nov;9(11):1518-20.
Chromatographic purity and assay of nicardipine by HPLC
C. V. Fernández  D. F. Mira  G. I. Luque
Journal of High Resolution Chromatography Volume13, Issue12 December 1990 Pages 846-849
Identification and characterization of a novel potential degradant and development and validation of stability-indicating rp-lc method for nicardipine impurities in injectable dosage form
Bhupendrasinh K. Vaghela  &Surendra Singh Rao
Journal of Liquid Chromatography & Related Technologies  Volume 36, 2013 - Issue 15 Pages 2166-2181