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Nicardipine Impurity 4

SZ目录编号 SZ-N004015
CAS 号 206976-29-6
分子式 C17H18N2O5
分子量 330.3
投资状态 Under Synthesis


化学名称: Dimethyl 2,6-dimethyl-4-(3-nitrosophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

微笑: O=C(C(C(C1=CC(N=O)=CC=C1)C(C(OC)=O)=C(C)N2)=C2C)OC

印地语: InChI=1/C29H32ClN3O7/c1-5-40-29(37)23-17(2)33-22(25(28(36)38-4)24(23)20-12-8-9-13-21(20)30)16-39-15-14-32-27(35)19-11-7-6-10-18(19)26(34)31-3/h6-13,24,33H,5,14-16H2,1-4H3,(H,31,34)(H,32,35)

Stability-indicating HPLC method for the determination of nicardipine in capsules and spiked human plasma. Identification of degradation products using HPLC/MS
Sheikha M.Al-Ghannam,Abeer M.Al-Olayan
Arabian Journal of Chemistry Volume 12, Issue 8, December 2019, Pages 1983-1993
 
Employing ionization behaviors to resolve a trace-level impurity: determination of 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5- pyridinedicarboxylic acid di-2-[methyl-(phenylmethyl)amino]ethyl ester in nicardipine drug substance
M B Maurin 1, R D Vickery, P Ma, J Manalo, M A Hussain
Pharm Res. 1992 Nov;9(11):1518-20.
 
Chromatographic purity and assay of nicardipine by HPLC
C. V. Fernández  D. F. Mira  G. I. Luque
Journal of High Resolution Chromatography Volume13, Issue12 December 1990 Pages 846-849
 
Identification and characterization of a novel potential degradant and development and validation of stability-indicating rp-lc method for nicardipine impurities in injectable dosage form
Bhupendrasinh K. Vaghela  &Surendra Singh Rao
Journal of Liquid Chromatography & Related Technologies  Volume 36, 2013 - Issue 15 Pages 2166-2181