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(E)-Teriflunomide

SZ目录编号 SZ-T015002
CAS 号 214782-56-6
分子式 C12H9F3N2O2
分子量 270.2
投资状态 Under Synthesis


化学名称: (E)-2-cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide

微笑: FC(F)(C1=CC=C(NC(/C(C#N)=C(O)\C)=O)C=C1)F

印地语: InChI=1S/C33H24Br2N4/c34-31(35)25-22-20-24(21-23-25)29-18-10-11-19-30(29)32-36-37-38-39(32)33(26-12-4-1-5-13-26,27-14-6-2-7-15-27)28-16-8-3-9-17-28/h1-23,31H

Quality-by-design-based development and validation of a stability-indicating UPLC method for quantification of teriflunomide in the presence of degradation products and its application to in-vitro dissolution
Nukendra Prasad Nadella,Venkata Nadh Ratnakaram & N. Srinivasu
Journal of Liquid Chromatography & Related Technologies Volume 40, 2017 - Issue 10 Pages 517-527
 
Development of Validated Stability Indicating HPTLC Method for the Estimation of Teriflunomide in Bulk and Tablet Dosage Form
Karmankar, Snehal; Tajne, M.
Current Pharmaceutical Analysis, Volume 16, Number 7, 2020, pp. 814-822(9)