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Abacavir 2-Hydroxy Impurity

SZ目录编号 SZ-A049010
CAS 号 NA
分子式 C14H20N6O2
分子量 304.4
投资状态 Custom Synthesis


化学名称: (1R,2R,4S)-2-(2-Amino-6-(cyclopropylamino)-9H-purin-9-yl)-4-(hydroxymethyl)cyclopentan-1-ol

微笑: NC1=NC(NC2CC2)=C3C(N([C@H]4[C@H](O)C[C@](CO)([H])C4)C=N3)=N1

印地语: InChI=1S/C11H12ClN5O.ClH/c12-9-8-10(16-11(13)15-9)17(5-14-8)7-2-1-6(3-7)4-18;/h1-2,5-7,18H,3-4H2,(H2,13,15,16);1H/t6-,7+;/m1./s1

Stability indicating RP-​HPLC method development and validation for determination of abacavir sulphate in tablet dosage form
By Ithape, Aniket B.; Deshpande, Padmanabh B.; Shelke, Priyanka
From International Journal of Pharmacy and Pharmaceutical Research (2020), 17(4), 670-680
 
A new stability indicating method was developed and validated for the simultaneous estimation of Lamivudine and Abacavir in tablet dosage form by RP-​HPLC
By Rajamahanti, Santoshi G.; Annapurna, N.; Santosh, T.; Durga, B.; Raziya, S. K.
From Research Journal of Pharmaceutical, Biological and Chemical Sciences (2017), 8(3), 407-421
 
A validated stability-​indicating RP-​HPLC method for abacavir sulfate in the presence of degradation products, its process-​related impurities and identification of oxidative degradant by LC-​MS​/MS
By Ragham, Pramod Kumar; Chandrasekhar, Kothapalli B.; Reddy, J. Rudraprasad; Kasturi, Krishna Mohan
From Indo American Journal of Pharmaceutical Research (2015), 5(1), 463-473