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Raltegravir Potassium

N° de SZ CAT SZ-R009011
Número CAS 871038-72-1
Mol.F. C20H20FKN6O5
Peso Molecular 482.5
Status de Fatura Custom Synthesis
Rel. CAS No 518048-05-0 (free base) ; 1292804-07-9 (Na salt)


Nome Químico: Potassium 4-[[(4-fluorophenyl)methyl]carbamoyl]-1-methyl-2-[2-(5-methyl-1,3,4-oxadiazole-2-carboxamido)propan-2-yl]-6-oxo-1,6-dihydropyrimidin-5-olate (as per EP); Potassium 4-[(4-fluorobenzyl)carbamoyl]-1-methyl-2-(1-methyl-1-{[(5-methyl-1,3,4-oxadiazol-2-yl)carbonyl]amino}ethyl)-6-oxo-1,6-dihydropyrimidin-5-olate (as per USP)

Sorrisos: CC(C)(C(N1C)=NC(C(NCC2=CC=C(F)C=C2)=O)=C(O[K])C1=O)NC(C3=NN=C(C)O3)=O

Inchi: InChI=1S/C35H43N7O5/c1-5-6-7-10-21-46-35(45)40-33(36)25-12-15-27(16-13-25)38-23-31-39-28-22-26(14-17-29(28)41(31)4)34(44)42(30-11-8-9-19-37-30)20-18-32(43)47-24(2)3/h8-9,11-17,19,22,24,38H,5-7,10,18,20-21,23H2,1-4H3,(H2,36,40,45)

Development and validation of stability indicating RP-​HPLC assay method of raltegravir in tablet dosage forms
By Shirisha, V.; Sairaju, B.; Illendula, Santhosh; Dutt, K. Rajeswar
From World Journal of Pharmacy and Pharmaceutical Sciences (2019), 8(10), 668-692
 
Stability indicating reverse-​phase high performance liquid chromatography method for the determination of raltegravir in bulk and pharmaceutical formulation
By Annapurna, Mukthinuthalapati Mathrusri; Teja, Gunnam Ravi; Hemchand, S.; Babu, R. Ravi Chandra
From International Journal of Green Pharmacy (2018), 12(1Suppl.), S177-S180
 
Development and validation of RP-​HPLC method for determination of raltegravir and its impurities in bulk drug and dosage forms
By Balaji, M.; AppaRao, K. M. Ch.; Ramakrishna, K.; Srinivasarao, V.
From Pharma Science Monitor (2014), 5(3Suppl.1), 187-196, 10 pp.