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Piperacillin EP Impurity D

N° de SZ CAT SZ-P048005
Número CAS 65772-67-0
Mol.F. C39H44N8O10S2
Peso Molecular 849.0
Status de Fatura In Stock


Nome Químico: (2S,5R,6R)-6-[(2R)-2-[(2S,5R,6R)-6-[(2R)-2-(4-ethyl-2,3-dioxopiperazine-1-carboxamido)-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxamido]-2- phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid (as per EP); (2S,5R,6R)-6-((R)-2-{(2S,5R,6R)-6-[(R)-2-(4-Ethyl-2,3-dioxopiperazine-1-carboxamido)-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxamido}-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid (as per USP)

Sinônimo: Piperacillinylampicillin

Sorrisos: O=C([C@@H](C(C)(C)S[C@]1([H])[C@@H]2NC([C@H](NC([C@@H](C(C)(C)S[C@]3([H])[C@@H]4NC([C@H](NC(N5C(C(N(CC)CC5)=O)=O)=O)C6=CC=CC=C6)=O)N3C4=O)=O)C7=CC=CC=C7)=O)N1C2=O)O

Inchi: InChI=1S/C22H29N5O6S/c1-4-26-10-11-27(19(30)18(26)29)21(33)25-15(13-8-6-5-7-9-13)17(28)23-12-14-24-16(20(31)32)22(2,3)34-14/h5-9,14-16,24H,4,10-12H2,1-3H3,(H,23,28)(H,25,33)(H,31,32)/t14?,15-,16+/m1/s1

Quantification of cefepime, meropenem, piperacillin, and tazobactam in human plasma using a sensitive and robust liquid chromatography-​tandem mass spectrometry method, part 2: stability evaluation
By D'cunha, Ronilda; Bach, Thanh; Young, Beth Ann; Li, Peizhi; Nalbant, Demet; Zhang, Jun; Winokur, Patricia; An, Guohua
From Antimicrobial Agents and Chemotherapy (2018), 62(9), e00861-18/1-e00861-18/9
 
Stability indicating RP-​HPLC method for the determination of Piperacillin and Tazobactam and their related substances in bulk and pharmaceutical formulation
By Navle, Khyathi; Prasanna, B. Lakshmi; Dometti, Hema Sree; Moodu, Shankar
From World Journal of Pharmacy and Pharmaceutical Sciences (2017), 6(8), 1760-1774

Therapeutic drug monitoring of beta-​lactam antibiotics - Influence of sample stability on the analysis of piperacillin, meropenem, ceftazidime and flucloxacillin by HPLC-​UV
By Pinder, Nadine; Brenner, Thorsten; Swoboda, Stefanie; Weigand, Markus A.; Hoppe-Tichy, Torsten
From Journal of Pharmaceutical and Biomedical Analysis (2017), 143, 86-93