Nome Químico: (2S,5R,6R)-6-[(2R)-2-(4-Ethyl-2,3-dioxopiperazine-1-carboxamido)-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid (as per EP); (2S,5R,6R)-6-[(R)-2-(4-Ethyl-2,3-dioxo-1-piperazinecarboxamido)-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid (as per USP)
Sorrisos: O=C([C@@H](C1=CC=CC=C1)NC(N(CCN(CC)C2=O)C2=O)=O)N[C@H]3[C@](SC(C)(C)[C@@H]4C(O)=O)([H])N4C3=O
Inchi: InChI=1/C13H13N3O3.H2O4S/c14-9-3-1-2-7-8(9)6-16(13(7)19)10-4-5-11(17)15-12(10)18;1-5(2,3)4/h1-3,10H,4-6,14H2,(H,15,17,18);(H2,1,2,3,4)
Quantification of cefepime, meropenem, piperacillin, and tazobactam in human plasma using a sensitive and robust liquid chromatography-tandem mass spectrometry method, part 2: stability evaluation
By D'cunha, Ronilda; Bach, Thanh; Young, Beth Ann; Li, Peizhi; Nalbant, Demet; Zhang, Jun; Winokur, Patricia; An, Guohua
From Antimicrobial Agents and Chemotherapy (2018), 62(9), e00861-18/1-e00861-18/9
Stability indicating RP-HPLC method for the determination of Piperacillin and Tazobactam and their related substances in bulk and pharmaceutical formulation
By Navle, Khyathi; Prasanna, B. Lakshmi; Dometti, Hema Sree; Moodu, Shankar
From World Journal of Pharmacy and Pharmaceutical Sciences (2017), 6(8), 1760-1774
Therapeutic drug monitoring of beta-lactam antibiotics - Influence of sample stability on the analysis of piperacillin, meropenem, ceftazidime and flucloxacillin by HPLC-UV
By Pinder, Nadine; Brenner, Thorsten; Swoboda, Stefanie; Weigand, Markus A.; Hoppe-Tichy, Torsten
From Journal of Pharmaceutical and Biomedical Analysis (2017), 143, 86-93