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Pemetrexed Impurity 18

N° de SZ CAT SZ-P014013
Número CAS 155405-81-5
Mol.F. C22H25N5O6
Peso Molecular 455.5
Status de Fatura In Stock
Rel. CAS No 1350616-69-1 (HCl salt)

Nome Químico: Dimethyl (4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoyl)-L-glutamate

Sinônimo: Pemetrexed Methyl Ester

Sorrisos: O=C1C2=C(NC(N)=N1)NC=C2CCC3=CC=C(C(N[C@H](C(OC)=O)CCC(OC)=O)=O)C=C3

Inchi: InChI=1S/C21H27O8P.2Na/c1-19-7-5-13(22)9-12(19)3-4-14-15-6-8-21(25,17(24)11-29-30(26,27)28)20(15,2)10-16(23)18(14)19;;/h5,7,9,14-15,18,25H,3-4,6,8,10-11H2,1-2H3,(H2,26,27,28);;/q;2*+1/p-2/t14-,15-,18+,19-,20-,21-;;/m0../s1

A stability-​indicating LC-​MS​/MS method optimization for Pemetrexed through design of experiments: Identification and characterization of major oxidative degradation product
By Narenderan, S. T.; Ramesh, J.; Babu, B.; Meyyanathan, S. N.
From Journal of Pharmaceutical and Biomedical Analysis (2020), 183, 113150
A new validated stability-​indicating gradient RP-​HPLC method for the determination of pemetrexed disodium and its process related substances
By Hemchand, S.; Babu, R. Ravi Chandra; Annapurna, Mukthinuthalapati Mathrusri
From Journal of Drug Delivery and Therapeutics (2019), 9(3Suppl.), 588-610

Content determination of related impurity-​L-​isomer in Pemetrexed Disodium for injection by HPLC
By Li, Jinhua; Yang, Mei
From Heilongjiang Yiyao (2014), 27(3), 498-500