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Palbociclib N-Glucuronide

N° de SZ CAT SZ-P015046
Número CAS NA
Mol.F. C30H37N7O8
Peso Molecular 623.7
Status de Fatura Under Synthesis


Nome Químico: (2R,4R,6S)-6-(4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazin-1-yl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid

Pharmacokinetic interaction study of novel combination of palbociclib and sorafenib for hepatocellular carcinoma in SD rats
David Paul, Patheparapu Chandrakala, Shruti Surendran, Prasanth Bitla, Nanjappan Satheeshkumar⁎
Journal of Chromatography B Volume 1108, 15 February 2019, Pages 25-31
 
Palbociclib Commercial Manufacturing Process Development. Part I: Control of Regioselectivity in a Grignard-Mediated SNAr Coupling
Shengquan Duan, David Place, Hahdi H. Perfect, Nathan D. Ide, Mark Thomas Maloney, Karen Sutherland, Kristin E. Price Wiglesworth, Ke Wang, Mark A. Olivier, Fangming Kong, Kyle R Leeman, Jon Blunt, John Draper, Marie McAuliffe, Maria M O'Sullivan, and Denis Lynch
Org. Process Res. Dev. 2016, 20, 7, 1191–1202