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Palbociclib Impurity 4

N° de SZ CAT SZ-P015005
Número CAS 1376615-91-6
Mol.F. C24H31N7O2
Peso Molecular 449.6
Status de Fatura Custom Synthesis


Nome Químico: Pyrido[2,​3-​d]​pyrimidin-​7(8H)​-​one, 8-​cyclopentyl-​6-​(1-​hydroxyethyl)​-​5-​methyl-​2-​[[5-​(1-​piperazinyl)​-​2-​pyridinyl]​amino]​-

Pharmacokinetic interaction study of novel combination of palbociclib and sorafenib for hepatocellular carcinoma in SD rats
David Paul, Patheparapu Chandrakala, Shruti Surendran, Prasanth Bitla, Nanjappan Satheeshkumar⁎
Journal of Chromatography B Volume 1108, 15 February 2019, Pages 25-31
 
Palbociclib Commercial Manufacturing Process Development. Part I: Control of Regioselectivity in a Grignard-Mediated SNAr Coupling
Shengquan Duan, David Place, Hahdi H. Perfect, Nathan D. Ide, Mark Thomas Maloney, Karen Sutherland, Kristin E. Price Wiglesworth, Ke Wang, Mark A. Olivier, Fangming Kong, Kyle R Leeman, Jon Blunt, John Draper, Marie McAuliffe, Maria M O'Sullivan, and Denis Lynch
Org. Process Res. Dev. 2016, 20, 7, 1191–1202