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Palbociclib Impurity 12

N° de SZ CAT SZ-P015013
Número CAS 2204368-69-2
Mol.F. C27H34ClN7O3
Peso Molecular 540.1
Status de Fatura Custom Synthesis


Nome Químico: Tert-butyl 4-(6-((2-chloro-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-6-yl)amino)pyridin-3-yl)piperazine-1-carboxylate

Pharmacokinetic interaction study of novel combination of palbociclib and sorafenib for hepatocellular carcinoma in SD rats
David Paul, Patheparapu Chandrakala, Shruti Surendran, Prasanth Bitla, Nanjappan Satheeshkumar⁎
Journal of Chromatography B Volume 1108, 15 February 2019, Pages 25-31
 
Palbociclib Commercial Manufacturing Process Development. Part I: Control of Regioselectivity in a Grignard-Mediated SNAr Coupling
Shengquan Duan, David Place, Hahdi H. Perfect, Nathan D. Ide, Mark Thomas Maloney, Karen Sutherland, Kristin E. Price Wiglesworth, Ke Wang, Mark A. Olivier, Fangming Kong, Kyle R Leeman, Jon Blunt, John Draper, Marie McAuliffe, Maria M O'Sullivan, and Denis Lynch
Org. Process Res. Dev. 2016, 20, 7, 1191–1202