Nome Químico: (5S,6R,7R,9R)-7-((benzoyloxy)(methyl)amino)-6-methoxy-5-methyl-6,7,8,9,15,16-hexahydro-5H,14H-17-oxa-4b,9a,15-triaza-5,9-methanodibenzo[b,h]cyclonona[jkl]cyclopenta[e]-as-indacen-14-one
Sinônimo: Midostaurin N-Benzoyloxy impurity
Sorrisos: O=C(ON(C)[C@]1([H])C[C@@]2([H])O[C@@](N3C4=C(C5=C3C=CC=C5)C6=C(C(NC6)=O)C7=C4N2C8=C7C=CC=C8)(C)[C@]1([H])OC)C9=CC=CC=C9
Inchi: InChI=1S/C35H30N4O5/c1-35-31(43-3)23(37(2)34(42)18-11-5-4-6-12-18)17-24(44-35)38-21-15-9-7-13-19(21)25-27-28(33(41)36-32(27)40)26-20-14-8-10-16-22(20)39(35)30(26)29(25)38/h4-16,23-24,31,33,41H,17H2,1-3H3,(H,36,40)/t23-,24-,31-,33?,35+/m1/s1
Impurity profiling and stability-indicating method development and validation for the estimation of assay and degradation impurities of midostaurin in softgel capsules using HPLC and LC-MS
By Lakka, Narasimha Swamy; Kuppan, Chandrasekar; Ravinathan, Poornima
From Biomedical Chromatography (2021), Ahead of Print.
RP-HPLC method development and validation for the estimation of midostaurin in bulk and pharmaceutical dosage form
By Harikrishnan, Narayanaswamy; Subramanian, Gejalakshmi; Hemalatha, C. N.; Pavankumar, V.
From International Journal of Research in Pharmaceutical Sciences (Madurai, India) (2020), 11(4), 5108-5112
Impurity profiling and stability-indicating method development and validation for the estimation of assay and degradation impurities of midostaurin in softgel capsules using HPLC and LC-MS
By Lakka Narasimha Swamy; Kuppan Chandrasekar; Ravinathan Poornima
From Biomedical chromatography : BMC (2021), e5222