Nome Químico: Diethyl (4-(N-methyl-4-(methylamino)benzamido)benzoyl)-L-glutamate
Sorrisos: CNC1=CC=C(C(N(C2=CC=C(C(N[C@H](C(OCC)=O)CCC(OCC)=O)=O)C=C2)C)=O)C=C1
Inchi: InChI=1S/C35H43N5O5/c1-38(34(42)29-13-11-26(12-14-29)25-39-19-15-28(16-20-39)33(36)41)21-24-40(44)22-17-30(18-23-40)45-35(43)37-32-10-6-5-9-31(32)27-7-3-2-4-8-27/h2-14,28,30H,15-25H2,1H3,(H2,36,41)(H,37,43)
Identification and Quantitation of Impurities in Methotrexate
dulal c. chatterji, altice g. frazier, and joseph f. gallell
Journal of Pharmaceutical Sciences Volume 67, Issue 5, May 1978, Pages 622-624
determination of methotrexate and its major metabolite, 7_hydroxymethotrexate, using capillary zone electrophoresis and laser-induced fluorescence detection
mark c. roach, philippe gozel and richard n. zare
Journal of Chromatography, 426 (1988) 129-140
Analytical methodologies for determination of methotrexate and its metabolites in pharmaceutical, biological and environmental samples
Forough Karami , Sara Ranjbar , Younes Ghasemi , Manica Negahdaripour
Journal of Pharmaceutical Analysis 9 (2019) 373-391
Perspectives of Methotrexate-Based Radioagents for Application in Nuclear Medicine
Paweł Krzysztof Halik,* Przemysław Kozmin ́ ski, and Ewa Gniazdowska
Mol. Pharmaceutics 2021, 18, 1, 33–43