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Bendamustine USP Related Compound H

N° de SZ CAT SZ-B010018
Número CAS 1228551-91-4
Mol.F. C32H41Cl3N6O4 
Peso Molecular  680.1
Status de Fatura In Stock
Rel. CAS No 1926162-37-9 (HCl salt)


Nome Químico: 4-[5-({2-[(4-{5-[Bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazol-2-yl}butanoyl)oxy]ethyl}(2-chloroethyl)amino)-1-methyl-1H-benzimidazol-2-yl]butanoic acid (as per USP)

Sorrisos: CN1C(CCCC(OCCN(C2=CC(N=C(CCCC(O)=O)N3C)=C3C=C2)CCCl)=O)=NC4=C1C=CC(N(CCCl)CCCl)=C4

Inchi: InChI=1S/C32H43ClN6O6.ClH/c1-36-28-12-10-24(22-26(28)34-29(36)5-3-7-31(42)43)39(16-19-41)17-20-45-32(44)8-4-6-30-35-25-21-23(9-11-27(25)37(30)2)38(14-13-33)15-18-40;/h9-12,21-22,40-41H,3-8,13-20H2,1-2H3,(H,42,43);1H

Polymorphic forms of bendamustine hydrochloride: crystal structure, thermal properties and stability at ambient conditions
By Gaztanaga, Pablo; Baggio, Ricardo; Vega, Daniel Roberto
From Acta Crystallographica, Section B: Structural Science, Crystal Engineering and Materials (2019), 75(6), 933-941
 
Development and validation of a stability-​indicating rp-​hplc method for the determination of bendamustine in raw material and finished product
By Dhananjaya, G.; Naveen, M.; Pathi, P. Janaki; Raghuram, J.; Raju, N. Appala
From World Journal of Pharmaceutical Research (2018), 7(18), 1172-1187
 
Novel validated RP-​HPLC method for bendamustine hydrochloride based on ion-​pair chromatography: application in determining infusion stability and pharmacokinetics
By Singh, Yuvraj; Chandrashekar, Anumandla; Pawar, Vivek K.; Saravanakumar, Veeramuthu; Meher, Jayagopal; Raval, Kavit; Singh, Pankaj; Kumar, R. Dinesh; Chourasia, Manish K.
From Journal of Chromatographic Science (2017), 55(1), 30-39

Stability- indicating novel HPLC method for estimation of Bendamustine in pharmaceutical forms
By Reddy, Gade Srinivas; Reddy, S. L. N. Prasad; Reddy, L. Shiva kumar
From American Journal of PharmTech Research (2016), 6(2), 343-357