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Bendamustine Nitro Ethyl Ester Impurity

N° de SZ CAT SZ-B010013
Número CAS 3543-72-4
Mol.F. C14H17N3O4
Peso Molecular 291.3
Status de Fatura Custom Synthesis
Rel. CAS No 1678557-24-8 (Sulfate salt)


Nome Químico: Ethyl 4-(1-methyl-5-nitro-1H-benzo[d]imidazol-2-yl)butanoate

Sorrisos: O=C(OCC)CCCC1=NC2=CC([N+]([O-])=O)=CC=C2N1C

Inchi: InChI=1S/C16H22ClN3O3.ClH/c1-19-14-6-5-12(20(8-7-17)9-10-21)11-13(14)18-15(19)3-2-4-16(22)23;/h5-6,11,21H,2-4,7-10H2,1H3,(H,22,23);1H

Polymorphic forms of bendamustine hydrochloride: crystal structure, thermal properties and stability at ambient conditions
By Gaztanaga, Pablo; Baggio, Ricardo; Vega, Daniel Roberto
From Acta Crystallographica, Section B: Structural Science, Crystal Engineering and Materials (2019), 75(6), 933-941
 
Development and validation of a stability-​indicating rp-​hplc method for the determination of bendamustine in raw material and finished product
By Dhananjaya, G.; Naveen, M.; Pathi, P. Janaki; Raghuram, J.; Raju, N. Appala
From World Journal of Pharmaceutical Research (2018), 7(18), 1172-1187
 
Novel validated RP-​HPLC method for bendamustine hydrochloride based on ion-​pair chromatography: application in determining infusion stability and pharmacokinetics
By Singh, Yuvraj; Chandrashekar, Anumandla; Pawar, Vivek K.; Saravanakumar, Veeramuthu; Meher, Jayagopal; Raval, Kavit; Singh, Pankaj; Kumar, R. Dinesh; Chourasia, Manish K.
From Journal of Chromatographic Science (2017), 55(1), 30-39

Stability- indicating novel HPLC method for estimation of Bendamustine in pharmaceutical forms
By Reddy, Gade Srinivas; Reddy, S. L. N. Prasad; Reddy, L. Shiva kumar
From American Journal of PharmTech Research (2016), 6(2), 343-357