Chemical Name: Cis-4-Phenyl-1,2,3,4-tetrahydro-N-methyl -1-naphthalen amine hydrochloride ;
Synonym: 3,4-Dideschloro Sertraline HCl (USP) ; cis-3,4-Dideschloro Sertraline HCl ; Sertraline Phenyl Impurity ;
Smiles: CN[C@H]1CC[C@@H](C2=CC=CC=C2)C3=C1C=CC=C3.Cl
Inchi: InChI=1S/C17H17Cl2N.ClH/c1-20-17-9-7-12(13-4-2-3-5-14(13)17)11-6-8-15(18)16(19)10-11;/h2-6,8,10,12,17,20H,7,9H2,1H3;1H/t12-,17+;/m0./s1
Separation of stereoisomers of sertraline and its related enantiomeric impurities on a dimethylated β-cyclodextrin stationary phase by HPLC
R. Nageswara Rao M.V.N. KumarTalluri Pawan K.Maurya
Journal of Pharmaceutical and Biomedical Analysis Volume 50, Issue 3, 15 October 2009, Pages 281-286
Development and validation of a HPLC method for the determination of sertraline and three non-chiral related impurities
Alessia Ferrarini , Angel Luis Huidobro, Federica Pellati, Coral Barbas
J Pharm Biomed Anal. 2010 Oct 10;53(2):122-9
UHPLC Determination of Enantiomeric Purity of Sertraline in the Presence of its Production Impurities
M. L. Reyes-Reyes, Gabriela Roa-Morales, Roberto Melgar-Fernández, Horacio Reyes-Pérez & Patricia Balderas-Hernández
Chromatographia volume 77, pages1315–1321(2014)