Chemical Name: 5-(4′-Methylbiphenyl-2-yl)-1H-tetrazole (as per EP)
Synonym: Losartan Methyl Impurity ; Irbesartan Methyl Impurity ; Candesartan Methyl Impurity
Smiles: CC(C=C1)=CC=C1C2=CC=CC=C2C3=NN=NN3
Inchi: InChI=1S/C8H11ClN2O/c1-2-3-4-7-10-6(5-12)8(9)11-7/h5H,2-4H2,1H3,(H,10,11)
Development and validation of a stability-indicating HPLC method for the simultaneous determination of Losartan potassium, hydrochlorothiazide, and their degradation products
Deanne L. Hertzog a,*, Jennifer Finnegan McCafferty b , Xueguang Fang b , R. Jeffrey Tyrrell c , Robert A. Reed
Journal of Pharmaceutical and Biomedical Analysis 30 (2002) 747–760
An Efficient, Commercially Viable, and Safe Process for Preparation of Losartan Potassium, an Angiotensin II Receptor Antagonist
Suri Babu Madasu,†,‡ N. A. Vekariya,*,† Ch Koteswaramma,† Aminul Islam,† Paul Douglas Sanasi,‡ and Raghu Babu Korupolu
Org. Process Res. Dev. 2012, 16, 12, 2025–2030