Chemical Name: (4S)-4,11-diethyl-4,12-dihydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-9-yl 1,4′-bipiperidine-1′-carboxylate (as per EP)
Synonym: 12-Hydroxy Irinotecan
Smiles: OC(C(C1=NC2=CC=C(OC(N3CCC(N4CCCCC4)CC3)=O)C=C52)=C5CC)N6C1=CC([C@](O)7CC)=C(COC7=O)C6=O
Inchi: InChI=1S/C24H24N2O5/c1-4-12-7-18-14(8-20(12)27)13(5-2)15-10-26-19(21(15)25-18)9-17-16(22(26)28)11-31-23(29)24(17,30)6-3/h7-9,27,30H,4-6,10-11H2,1-3H3/t24-/m0/s1
RP-HPLC method development and validation for the simultaneous estimation of Irinotecan hydrochloride and Capecitabine in Active Pharmaceutical Ingredients (APIs)
By Vijaya Jyothi, M.; Bhargav, E.; Keerthana, B.; Varalakshmi, Devi K.
From International Journal of Research in Pharmaceutical Sciences (Madurai, India) (2018), 9(1), 63-67
Method development, validation and forced degradation studies of Irinotecan in bulk and pharmaceutical dosage form
By Swathi, Koduru; Farooqui, Tahmeena; Muntaha, Sidra Tul; Ayesha, Syeda Amtul; Shama, Syeda; Siddiqui, Sarah Imam
From World Journal of Pharmacy and Pharmaceutical Sciences (2018), 7(8), 996-1009