Chemical Name: (6S,8S,9R,10S,11S,13S,14S)-17-(2-Chloroacetyl)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15-decahydro-3H-cyclopenta[a]phenanthren-3-one
Synonym: 6-Chloro halobetasol propionate ; 6a-Desfluoro-6a-chloro Halobetasol Propionate
Smiles: O=C1C=C[C@@]2(C)C([C@@H](F)C[C@]3([H])[C@]2(F)[C@@H](O)C[C@@]4(C)[C@@]3([H])CC(C)=C4C(CCl)=O)=C1
Inchi: InChI=1S/C25H31Cl2FO5/c1-5-21(32)33-25(20(31)12-26)13(2)8-15-16-10-18(28)17-9-14(29)6-7-22(17,3)24(16,27)19(30)11-23(15,25)4/h6-7,9,13,15-16,18-19,30H,5,8,10-12H2,1-4H3/t13-,15-,16-,18-,19-,22-,23-,24-,25-/m0/s1
Quantification of halobetasol propionate and its impurities present in topical dosage forms by stability-indicating LC method
By Nalwade, Santaji; Reddy, Vangala Ranga; Kulkarni, Dipak; Todamal, Sandip
From Journal of Chromatographic Science (2015), 53(1), 127-134
Impurity profiling and a stability-indicating UPLC method development and validation for the estimation of related impurities of halobetasol propionate in halobetasol propionate 0.05% (w/w) cream
By Prakash, Lakkireddy; Malipeddi, H.; Subbaiah, Venkata B.; Lakka, Narasimha S.
From Journal of Chromatographic Science (2015), 53(1), 112-121
Spectrophotometric determination of clobetasol propionate, halobetasol propionate, quinagolide hydrochloride, through charge transfer complexation
By Mostafa Azza A; Bebawy Lories I; Refaat Heba H
From Journal of pharmaceutical and biomedical analysis (2002), 27(6), 889-99