Chemical Name: Methyl ((R)-2-((2S,4S)-2-(5-(2-((2S,5S)-1-((methoxycarbonyl)-L-valyl)-5-methylpyrrolidin-2-yl)-1,11-dihydroisochromeno[4',3':6,7]naphtho[1,2-d]imidazol-9-yl)-1H-imidazol-2-yl)-4-(methoxymethyl)pyrrolidin-1-yl)-2-oxo-1-phenylethyl)carbamate Dihydrochloride
Smiles: COC[C@H]1C[C@@H](C2=NC=C(C3=CC4=C(C5=CC6=CC=C7C(NC([C@H]8N(C([C@@H](NC(OC)=O)C(C)C)=O)[C@@H](C)CC8)=N7)=C6C=C5OC4)C=C3)N2)N(C([C@H](NC(OC)=O)C9=CC=CC=C9)=O)C1.[2HCl]
Inchi: InChI=1/C66H89N13O24S6/c1-5-49(84)68-31(2)56(92)75-48-30-105-104-25-37-22-50(85)78-63(99)44(69-33(4)81)26-106-108-28-46(61(97)72-41(23-53(89)90)55(91)36-8-6-7-9-36)77-62(98)47(76-59(95)42(20-34-10-14-38(82)15-11-34)73-58(94)40(71-57(37)93)18-19-52(87)88)29-109-107-27-45(70-51(86)24-67-65(101)54(32(3)80)79-64(48)100)60(96)74-43(66(102)103)21-35-12-16-39(83)17-13-35/h10-17,31-32,36-37,40-48,54,80,82-83H,5-9,18-30H2,1-4H3,(H,67,101)(H,68,84)(H,69,81)(H,70,86)(H,71,93)(H,72,97)(H,73,94)(H,74,96)(H,75,92)(H,76,95)(H,77,98)(H,79,100)(H,87,88)(H,89,90)(H,102,103)(H,78,85,99)
UPLC Separation of forced degradation and process related impurities of Velpatasvir and structure elucidation by online LC-Quadrupole-Time of flight-Tandem mass Spectrometry
Md. Sattar Abdul*, Suneetha A.Research Journal of Pharmacy and Technology
Year : 2019, Volume : 12, Issue : 2
First page : ( 477) Last page : ( 482)
Stability indicating RP-HPLC Method development and Validation for the Estimation of Sofosbuvir, Velpatasvir and Voxilaprevir in Bulk and Pharmaceutical dosage form
Kokkirala, Tej Kumar; Suryakala, Duvvuri. Research Journal of Pharmacy and Technology; RaipurVol. 13, Iss. 11, (Nov 2020): 5063-5071. DOI:10.5958/0974-360X.2020.00887.2
RP-HPLC Method Development and Validation for Velpatasvir and Voxilaprevir by Simultaneous Determination in Bulk and Their Pharmaceutical Dosage Forms
DebasishSwainaAmrej SinghYadavaChandrasekharSasapuaVenkatakrishnaAkulabGananadhamuSamanthulaa
Microchemical JournalVolume 155, June 2020, 104657