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Sapropterin Nitroso Impurity 1

SZ CAT No SZ-S027022
CAS No NA
Mol.F. C9H13N7O5
Mol.Wt. 299.2
Inv. Status Custom Synthesis


Chemical Name: (R)-2-Amino-6-((1R,2S)-1,2-dihydroxypropyl)-5,8-dinitroso-5,6,7,8-tetrahydropteridin-4(1H)-one

HPLC-Based Analysis of Impurities in Sapropterin Branded and Generic Tablet
Emanuela Scudellaro, Luciana Tartaglione, Fabio Varriale, Carmela Dell’Aversano, and Orazio Taglialatela-Scafati
Pharmaceutics. 2020 Apr; 12(4): 323.
 
Sapropterin Dihydrochloride Mixed With Common Foods and Beverages
Elaina R. Jurecki, MS, RD;Amy Cunningham, MS, RD, LDN; John J. Mahoney, BA;Douglas Tingley, BS; Stanley Chung, BS;Neil James, BSc (Hons); Jessica L. Cohen-Pfeffer, MD
Top Clin Nutr Vol. 29, No. 4, pp. 325–331
 
Recommendations for the use of sapropterin in phenylketonuria
AmyCunningham, aHeatherBausell, MaryBrown, Maggie, hapmandKariD, FouweSharonErnst, JulieMcClure, HelenMcCune, DonnaO'Steen, AmyPender, JillSkrabal, AnnWessel, ElainaJurecki, RenéeShediac, SuyashPrasad, JaneGillis, StephenCederbaum
Molecular Genetics and Metabolism, Volume 106, Issue 3, July 2012, Pages 269-276