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Sapropterin Impurity 1

SZ CAT No SZ-S027019
CAS No 2098644-02-9
Mol.F. C10H13N5O4
Mol.Wt. 267.2
Inv. Status Custom Synthesis


Chemical Name: 2-Amino-6-((1R,2S)-1,2-dihydroxypropyl)-7-(hydroxymethyl)pteridin-4(3H)-one

HPLC-Based Analysis of Impurities in Sapropterin Branded and Generic Tablet
Emanuela Scudellaro, Luciana Tartaglione, Fabio Varriale, Carmela Dell’Aversano, and Orazio Taglialatela-Scafati
Pharmaceutics. 2020 Apr; 12(4): 323.
 
Sapropterin Dihydrochloride Mixed With Common Foods and Beverages
Elaina R. Jurecki, MS, RD;Amy Cunningham, MS, RD, LDN; John J. Mahoney, BA;Douglas Tingley, BS; Stanley Chung, BS;Neil James, BSc (Hons); Jessica L. Cohen-Pfeffer, MD
Top Clin Nutr Vol. 29, No. 4, pp. 325–331
 
Recommendations for the use of sapropterin in phenylketonuria
AmyCunningham, aHeatherBausell, MaryBrown, Maggie, hapmandKariD, FouweSharonErnst, JulieMcClure, HelenMcCune, DonnaO'Steen, AmyPender, JillSkrabal, AnnWessel, ElainaJurecki, RenéeShediac, SuyashPrasad, JaneGillis, StephenCederbaum
Molecular Genetics and Metabolism, Volume 106, Issue 3, July 2012, Pages 269-276