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Salbutamol EP impurity H Hydrochloride

SZ CAT No SZ-S003044
CAS No 2252153-95-8
Mol.F. C13H21NO : HCl
Mol.Wt. 207.3 : 36.5
Inv. Status Custom Synthesis
Rel. CAS No 132183-64-3 (free base)


Chemical Name: 4-[2-[(1,1-dimethylethyl)amino]ethyl]-2-methylphenol Hydrochloride (as per EP)

Synonym: Salbutamol BP Impurity H ; Salbutamol Dideshydroxy Impurity

A Combined High-Throughput Screening and Reaction Profiling Approach Toward Development of a Tandem Catalytic Hydrogenation for the Synthesis of Salbutamol
David C. Leitch, Thomas F. Greene, Roisin O'Keeffe, Thomas Lovelace, Jeremiah D Powers, and Andrew D. Searle
Org. Process Res. Dev. 2017, 21, 11, 1806–1814
 
Determination of salbutamol-related impurities by capillary electrophoresis
K.D. Altria
Journal of Chromatography, 634 (1993) 323-328
 
Development and Validation of RP-HPLC Method for Simultaneous Determination of Guaifenesin Impurities in Multi Drug Combinations
Development and Validation of RP-HPLC Method for Simultaneous Determination of Guaifenesin Impurities in Multi Drug Combinations
Global Journal of Medical research: B Pharma, Drug Discovery, Toxicology and Medicine Volume 14 Issue 2 Version 1.0 Year 2014