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Quetiapine EP Impurity I HCl Salt

SZ CAT No SZ-Q001010
CAS No 329218-14-6
Mol.F. C19H21N3OS : 2HCl
Mol.Wt. 339.5 : 2(36.5)
Inv. Status In Stock
Rel. CAS No 329216-67-3 (free base)


Chemical Name: 11-[4-(2-Hydroxyethyl)-1-piperazinyl]-dibenzo[b,f][1,4]thiazepine dihydrochloride

Synonym: Quetiapine Desethoxy Impurity (USP) ; Quetiapine Alcohol Impurity ; Quetiapine Ethanol Impurity

Identification and Characterization of Potential Impurities of Quetiapine Fumarate
Elżbieta U. Stolarczyk,Łukasz Kaczmarek,Kamil Eksanow,Marek Kubiszewski,Magdalena Glice &Andrzej Kutner
Pharmaceutical Development and Technology  Volume 14, 2009 - Issue 1 Pages 29-39
 
An Improved and Single Pot Process for the Production of Quetiapine Hemifumarate Substantially Free from Potential Impurities
Navnath C. Niphade, Anil C. Mali, Bhushan S. Pandit, Kunal M. Jagtap, Sanjay A. Jadhav, Madhukar N. Jachak, and Vijayavitthal T. Mathad
Org. Process Res. Dev. 2009, 13, 4, 792–797
 
Stability indicating fast LC method for determination of quetiapine fumarate related substances in bulk and pharmaceutical formulation
R.Narendra Kumar, *G.Nageswara Rao, P.Y.Naidu
Der Pharmacia Lettre, 2011, 3(3): 457-469