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Prednisolone Impurity C

SZ CAT No SZ-P027048
CAS No 3754-05-0
Mol.F. C21H26O6
Mol.Wt. 374.4
Inv. Status Custom Synthesis


Chemical Name: (8S,9S,10R,13S,14S,16R,17S)-16,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,10,12,13,14,15,16,17-decahydro-3H-cyclopenta[a]phenanthrene-3,11(6H)-dione

Synonym: 11-Ketone-16-alphahydroxy prednisolone

Smiles: C[C@@]12C(CC[C@]([C@@](C[C@@H](O)[C@]3(O)C(CO)=O)([H])[C@]3(C)C4)([H])[C@]2([H])C4=O)=CC(C=C1)=O

Inchi: InChI=1S/C21H28O6/c1-19-6-5-12(23)7-11(19)3-4-13-14-8-16(25)21(27,10-22)18(26)20(14,2)9-15(24)17(13)19/h5-7,13-17,22,24-25,27H,3-4,8-10H2,1-2H3/t13-,14-,15-,16+,17+,19-,20-,21+/m0/s1

Validated stability indicating RP-​LC assay for determination of gatifloxacin and prednisolone acetatein ophthalmic preparations and biological samples
By Qadir, Muhammad A.; Shahzad, Shabnam; Ahmed, Mahmood; Razzaq, Syed S.; Shafiq, Muhmmad I.
From Latin American Journal of Pharmacy (2016), 35(5), 912-920
 
Novel stability indicating RP-​HPLC method for the simultaneous estimation of moxifloxacin and prednisolone in bulk and their combined dosage form
By Potnuri, Naga Raju; Rao, G. Devala; Prasad, Y. Rajendra
From International Journal of Pharmaceutical Sciences and Research (2015), 6(5), 1965-1973
 
Development and validation of a new stability indicating reversed phase liquid chromatographic method for the determination of prednisolone acetate and impurities in an ophthalmic suspension
By Marley, Adrian; Stalcup, Apryll M.; Connolly, Damian
From Journal of Pharmaceutical and Biomedical Analysis (2015), 102, 261-266