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Prednisolone EP Impurity A Hydrochloride

SZ CAT No SZ-P027033
CAS No 393782-60-0
Mol.F. C21H30O5 : HCl
Mol.Wt. 362.5 : 36.5
Inv. Status Custom Synthesis
Rel. CAS No 50-23-7 (free base)


Chemical Name: 11β,17,21-Trihydroxypregn-4-ene-3,20-dione Hydrochloride (as per EP)

Smiles: C[C@@]1([C@@]2(O)C(CO)=O)[C@](CC2)([H])[C@@](CCC3=CC4=O)([H])[C@]([C@]3(CC4)C)([H])[C@@H](O)C1.Cl

Inchi: InChI=1S/C21H23I4NO9/c22-10-4-9(5-11(23)17(10)30)35-20-12(24)1-8(2-13(20)25)3-14(21(33)34)26-6-15(28)18(31)19(32)16(29)7-27/h1-2,4-5,14-16,18-19,26-32H,3,6-7H2,(H,33,34)/t14-,15+,16+,18+,19+/m0/s1

Validated stability indicating RP-​LC assay for determination of gatifloxacin and prednisolone acetatein ophthalmic preparations and biological samples
By Qadir, Muhammad A.; Shahzad, Shabnam; Ahmed, Mahmood; Razzaq, Syed S.; Shafiq, Muhmmad I.
From Latin American Journal of Pharmacy (2016), 35(5), 912-920
 
Novel stability indicating RP-​HPLC method for the simultaneous estimation of moxifloxacin and prednisolone in bulk and their combined dosage form
By Potnuri, Naga Raju; Rao, G. Devala; Prasad, Y. Rajendra
From International Journal of Pharmaceutical Sciences and Research (2015), 6(5), 1965-1973
 
Development and validation of a new stability indicating reversed phase liquid chromatographic method for the determination of prednisolone acetate and impurities in an ophthalmic suspension
By Marley, Adrian; Stalcup, Apryll M.; Connolly, Damian
From Journal of Pharmaceutical and Biomedical Analysis (2015), 102, 261-266