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Prednisolone D-homo Derivative

SZ CAT No SZ-P027056
CAS No 1201919-18-7
Mol.F. C22H28FNa2O8P
Mol.Wt. 516.4
Inv. Status Custom Synthesis
Rel. CAS No 1202002-01-4 (Free base)


Chemical Name: Sodium ((1S,3S,10aS,10bR,11S,12aS)-10b-fluoro-1,11-dihydroxy-3,10a,12a-trimethyl-2,8-dioxo-1,2,3,4,4a,4b,5,6,8,10a,10b,11,12,12a-tetradecahydrochrysen-1-yl)methyl phosphate

Smiles: O=C1C=C[C@@]2(C)C(CCC3[C@]2(F)[C@@H](O)C[C@@]4(C)C3C[C@H](C)C([C@@]4(O)COP(O[Na])(O[Na])=O)=O)=C1

Inchi: InChI=1S/C21H29O8P/c1-19-8-7-13(22)9-12(19)3-4-14-15-5-6-17(24)21(25,11-29-30(26,27)28)20(15,2)10-16(23)18(14)19/h7-9,14-16,18,23,25H,3-6,10-11H2,1-2H3,(H2,26,27,28)/t14-,15-,16-,18+,19-,20-,21-/m0/s1

Validated stability indicating RP-​LC assay for determination of gatifloxacin and prednisolone acetatein ophthalmic preparations and biological samples
By Qadir, Muhammad A.; Shahzad, Shabnam; Ahmed, Mahmood; Razzaq, Syed S.; Shafiq, Muhmmad I.
From Latin American Journal of Pharmacy (2016), 35(5), 912-920
 
Novel stability indicating RP-​HPLC method for the simultaneous estimation of moxifloxacin and prednisolone in bulk and their combined dosage form
By Potnuri, Naga Raju; Rao, G. Devala; Prasad, Y. Rajendra
From International Journal of Pharmaceutical Sciences and Research (2015), 6(5), 1965-1973
 
Development and validation of a new stability indicating reversed phase liquid chromatographic method for the determination of prednisolone acetate and impurities in an ophthalmic suspension
By Marley, Adrian; Stalcup, Apryll M.; Connolly, Damian
From Journal of Pharmaceutical and Biomedical Analysis (2015), 102, 261-266