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Posaconazole N-β-D-Glucuronide 

SZ CAT No SZ-P022114
CAS No NA
Mol.F. C43H50F2N8O10
Mol.Wt. 876.9
Inv. Status Custom Synthesis


Chemical Name: (2S,4R,5R)-6-(1-(((2R,4R)-2-(2,4-difluorophenyl)-4-((4-(4-(4-(1-((2S,3S)-2-hydroxypentan-3-yl)-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl)phenyl)piperazin-1-yl)phenoxy)methyl)tetrahydrofuran-2-yl)methyl)-1H-1,2,4-triazol-4-ium-4-yl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylate

Smiles: O=C1N(C2=CC=C(N3CCN(C4=CC=C(OC[C@@]5([H])C[C@@](C6=C(F)C=C(F)C=C6)(CN7N=C[N+](C8O[C@H](C([O-])=O)C(O)[C@@H](O)[C@H]8O)=C7)OC5)C=C4)CC3)C=C2)C=NN1[C@@H](CC)[C@@H](O)C

Inchi: InChI=1S/C43H50F2N8O10/c1-3-35(26(2)54)53-42(60)52(24-47-53)31-7-5-29(6-8-31)48-14-16-49(17-15-48)30-9-11-32(12-10-30)61-20-27-19-43(62-21-27,33-13-4-28(44)18-34(33)45)22-51-25-50(23-46-51)40-38(57)36(55)37(56)39(63-40)41(58)59/h4-13,18,23-27,35-40,54-57H,3,14-17,19-22H2,1-2H3/t26-,27+,35-,36-,37-,38+,39-,40+,43-/m0/s1

Influence of cyclodextrin on posaconazole stability, release and activity: Improve the utility of the drug
By Santana, Ana Cristina Sousa Gramoza Vilarinho; Nadvorny, Daniela; da Rocha Passos, Taisa Daiany; de La Roca Soares, Monica Felts; Soares-Sobrinho, Jose Lamartine
From Journal of Drug Delivery Science and Technology (2019), 53, 101153
 
Stability-​indicating HPLC method development and structural elucidation of novel degradation products in posaconazole injection by LC-​TOF​/MS, LC-​MS​/MS and NMR
By Yang, Yidi; Zhu, Xi; Zhang, Fei; Li, Wei; Wu, Ying; Ding, Li
From Journal of Pharmaceutical and Biomedical Analysis (2016), 125, 165-177
 
Stability indicating HPLC method for the quantification of posaconazole and its related substances
By Govind, Sampath Kumar Reddy; Nagaraju, Ch. V. S.; Rajan, S. T.; Eshwaraiah, S.; Kishore, M.; Rakesh, M.; Chakravarthy, I. E.
From Pharma Chemica (2014), 6(1), 486-494, 9 pp..