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Posaconazole Impurity 9

SZ CAT No SZ-P022029
CAS No NA
Mol.F. C23H23FN6O4S 
Mol.Wt. 498.5
Inv. Status Under Synthesis


Chemical Name: ((3S,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2-fluoro-4-(1H-1,2,4-triazol-1-yl)phenyl)tetrahydrofuran-3-yl)methyl 4-methylbenzenesulfonate

Smiles: FC1=C([C@@]2(CN3C=NC=N3)C[C@H](COS(=O)(C4=CC=C(C)C=C4)=O)CO2)C=CC(N5C=NC=N5)=C1

Inchi: InChI=1S/C29H37N5O3/c1-3-28(22(2)37-21-23-7-5-4-6-8-23)31-32-29(36)30-24-9-11-25(12-10-24)33-17-19-34(20-18-33)26-13-15-27(35)16-14-26/h4-16,22,28,31,35H,3,17-21H2,1-2H3,(H2,30,32,36)/t22-,28-/m0/s1

Influence of cyclodextrin on posaconazole stability, release and activity: Improve the utility of the drug
By Santana, Ana Cristina Sousa Gramoza Vilarinho; Nadvorny, Daniela; da Rocha Passos, Taisa Daiany; de La Roca Soares, Monica Felts; Soares-Sobrinho, Jose Lamartine
From Journal of Drug Delivery Science and Technology (2019), 53, 101153
 
Stability-​indicating HPLC method development and structural elucidation of novel degradation products in posaconazole injection by LC-​TOF​/MS, LC-​MS​/MS and NMR
By Yang, Yidi; Zhu, Xi; Zhang, Fei; Li, Wei; Wu, Ying; Ding, Li
From Journal of Pharmaceutical and Biomedical Analysis (2016), 125, 165-177
 
Stability indicating HPLC method for the quantification of posaconazole and its related substances
By Govind, Sampath Kumar Reddy; Nagaraju, Ch. V. S.; Rajan, S. T.; Eshwaraiah, S.; Kishore, M.; Rakesh, M.; Chakravarthy, I. E.
From Pharma Chemica (2014), 6(1), 486-494, 9 pp..