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Posaconazole Impurity 89

SZ CAT No SZ-P022127
Mol.F. C36H44F2N8O4
Mol.Wt. 690.8
Inv. Status Custom Synthesis

Chemical Name: N-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2R,3S)-2-hydroxypentan-3-yl)hydrazine-1-carboxamide

Smiles: FC1=CC(F)=CC=C1[C@](C2)(CN3C=NC=N3)OC[C@H]2COC4=CC=C(C=C4)N5CCN(C6=CC=C(NC(N(N)[C@@H](CC)[C@H](O)C)=O)C=C6)CC5

Inchi: InChI=1S/C36H44F2N8O4/c1-3-34(25(2)47)46(39)35(48)42-28-5-7-29(8-6-28)43-14-16-44(17-15-43)30-9-11-31(12-10-30)49-20-26-19-36(50-21-26,22-45-24-40-23-41-45)32-13-4-27(37)18-33(32)38/h4-13,18,23-26,34,47H,3,14-17,19-22,39H2,1-2H3,(H,42,48)/t25-,26-,34-,36-/m0/s1

Influence of cyclodextrin on posaconazole stability, release and activity: Improve the utility of the drug
By Santana, Ana Cristina Sousa Gramoza Vilarinho; Nadvorny, Daniela; da Rocha Passos, Taisa Daiany; de La Roca Soares, Monica Felts; Soares-Sobrinho, Jose Lamartine
From Journal of Drug Delivery Science and Technology (2019), 53, 101153
Stability-​indicating HPLC method development and structural elucidation of novel degradation products in posaconazole injection by LC-​TOF​/MS, LC-​MS​/MS and NMR
By Yang, Yidi; Zhu, Xi; Zhang, Fei; Li, Wei; Wu, Ying; Ding, Li
From Journal of Pharmaceutical and Biomedical Analysis (2016), 125, 165-177
Stability indicating HPLC method for the quantification of posaconazole and its related substances
By Govind, Sampath Kumar Reddy; Nagaraju, Ch. V. S.; Rajan, S. T.; Eshwaraiah, S.; Kishore, M.; Rakesh, M.; Chakravarthy, I. E.
From Pharma Chemica (2014), 6(1), 486-494, 9 pp..