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Posaconazole Impurity 78

SZ CAT No SZ-P022112
CAS No 2514953-93-4
Mol.F. C17H25N5O2
Mol.Wt. 331.4
Inv. Status Out of Stock


Chemical Name: 2-((2S,3S)-2-hydroxypentan-3-yl)-4-(4-(piperazin-1-yl)phenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one

Smiles: O=C1N(C2=CC=C(N3CCNCC3)C=C2)C=NN1[C@@H](CC)[C@@H](O)C

Inchi: InChI=1S/C37H36F2N6O4/c38-28-6-15-34(35(39)20-28)37(24-45-26-40-25-41-45)21-27(23-48-37)22-47-32-13-11-31(12-14-32)44-18-16-43(17-19-44)30-9-7-29(8-10-30)42-36(46)49-33-4-2-1-3-5-33/h1-15,20,25-27H,16-19,21-24H2,(H,42,46)/t27-,37+/m1/s1

Influence of cyclodextrin on posaconazole stability, release and activity: Improve the utility of the drug
By Santana, Ana Cristina Sousa Gramoza Vilarinho; Nadvorny, Daniela; da Rocha Passos, Taisa Daiany; de La Roca Soares, Monica Felts; Soares-Sobrinho, Jose Lamartine
From Journal of Drug Delivery Science and Technology (2019), 53, 101153
 
Stability-​indicating HPLC method development and structural elucidation of novel degradation products in posaconazole injection by LC-​TOF​/MS, LC-​MS​/MS and NMR
By Yang, Yidi; Zhu, Xi; Zhang, Fei; Li, Wei; Wu, Ying; Ding, Li
From Journal of Pharmaceutical and Biomedical Analysis (2016), 125, 165-177
 
Stability indicating HPLC method for the quantification of posaconazole and its related substances
By Govind, Sampath Kumar Reddy; Nagaraju, Ch. V. S.; Rajan, S. T.; Eshwaraiah, S.; Kishore, M.; Rakesh, M.; Chakravarthy, I. E.
From Pharma Chemica (2014), 6(1), 486-494, 9 pp..