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Posaconazole Impurity 72

SZ CAT No SZ-P022106
CAS No 169436-60-6
Mol.F. C14H15F2IO3
Mol.Wt. 396.2
Inv. Status Under Synthesis

Chemical Name: ((3S,5R)-5-(2,4-difluorophenyl)-5-(iodomethyl)tetrahydrofuran-3-yl)methyl acetate

Smiles: IC[C@]1(C(C=CC(F)=C2)=C2F)C[C@H](COC(C)=O)CO1

Inchi: InChI=1/C19H24O4S/c1-4-19(16(3)22-14-17-8-6-5-7-9-17)23-24(20,21)18-12-10-15(2)11-13-18/h5-13,16,19H,4,14H2,1-3H3

Influence of cyclodextrin on posaconazole stability, release and activity: Improve the utility of the drug
By Santana, Ana Cristina Sousa Gramoza Vilarinho; Nadvorny, Daniela; da Rocha Passos, Taisa Daiany; de La Roca Soares, Monica Felts; Soares-Sobrinho, Jose Lamartine
From Journal of Drug Delivery Science and Technology (2019), 53, 101153
Stability-​indicating HPLC method development and structural elucidation of novel degradation products in posaconazole injection by LC-​TOF​/MS, LC-​MS​/MS and NMR
By Yang, Yidi; Zhu, Xi; Zhang, Fei; Li, Wei; Wu, Ying; Ding, Li
From Journal of Pharmaceutical and Biomedical Analysis (2016), 125, 165-177
Stability indicating HPLC method for the quantification of posaconazole and its related substances
By Govind, Sampath Kumar Reddy; Nagaraju, Ch. V. S.; Rajan, S. T.; Eshwaraiah, S.; Kishore, M.; Rakesh, M.; Chakravarthy, I. E.
From Pharma Chemica (2014), 6(1), 486-494, 9 pp..