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Posaconazole Impurity 7

SZ CAT No SZ-P022027
CAS No 345217-02-9
Mol.F. C29H37N5O3 
Mol.Wt. 503.7
Inv. Status Custom Synthesis


Chemical Name: 1-((2S,3S)-2-(benzyloxy)pentan-3-yl)-N-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)hydrazine-1-carboxamide

Smiles: OC1=CC=C(N2CCN(C3=CC=C(NC(N([C@@H](CC)[C@@H](OCC4=CC=CC=C4)C)N)=O)C=C3)CC2)C=C1

Inchi: InChI=1S/C30H37N5O4/c1-3-29(23(2)39-21-24-7-5-4-6-8-24)35(31-22-36)30(38)32-25-9-11-26(12-10-25)33-17-19-34(20-18-33)27-13-15-28(37)16-14-27/h4-16,22-23,29,37H,3,17-21H2,1-2H3,(H,31,36)(H,32,38)/t23-,29-/m0/s1

Influence of cyclodextrin on posaconazole stability, release and activity: Improve the utility of the drug
By Santana, Ana Cristina Sousa Gramoza Vilarinho; Nadvorny, Daniela; da Rocha Passos, Taisa Daiany; de La Roca Soares, Monica Felts; Soares-Sobrinho, Jose Lamartine
From Journal of Drug Delivery Science and Technology (2019), 53, 101153
 
Stability-​indicating HPLC method development and structural elucidation of novel degradation products in posaconazole injection by LC-​TOF​/MS, LC-​MS​/MS and NMR
By Yang, Yidi; Zhu, Xi; Zhang, Fei; Li, Wei; Wu, Ying; Ding, Li
From Journal of Pharmaceutical and Biomedical Analysis (2016), 125, 165-177
 
Stability indicating HPLC method for the quantification of posaconazole and its related substances
By Govind, Sampath Kumar Reddy; Nagaraju, Ch. V. S.; Rajan, S. T.; Eshwaraiah, S.; Kishore, M.; Rakesh, M.; Chakravarthy, I. E.
From Pharma Chemica (2014), 6(1), 486-494, 9 pp..