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Posaconazole Impurity 24

SZ CAT No SZ-P022044
Mol.F. C21H21F2N3O4S
Mol.Wt. 449.5
Inv. Status Under Synthesis

Chemical Name: ((3S,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,6-difluorophenyl)tetrahydrofuran-3-yl)methyl 4-methylbenzenesulfonate

Smiles: O=S(C1=CC=C(C)C=C1)(OC[C@@H]2CO[C@](C3=C(F)C=CC=C3F)(CN4N=CN=C4)C2)=O

Inchi: InChI=1S/C35H38F2N8O5/c1-3-33(23(2)46)45-34(47)44(22-41-45)27-7-5-26(6-8-27)42-13-12-39-32-11-9-28(14-24(32)16-42)48-17-29-18-49-35(50-29,19-43-21-38-20-40-43)30-10-4-25(36)15-31(30)37/h4-11,14-15,20-23,29,33,39,46H,3,12-13,16-19H2,1-2H3/t23-,29+,33-,35+/m0/s1

Influence of cyclodextrin on posaconazole stability, release and activity: Improve the utility of the drug
By Santana, Ana Cristina Sousa Gramoza Vilarinho; Nadvorny, Daniela; da Rocha Passos, Taisa Daiany; de La Roca Soares, Monica Felts; Soares-Sobrinho, Jose Lamartine
From Journal of Drug Delivery Science and Technology (2019), 53, 101153
Stability-​indicating HPLC method development and structural elucidation of novel degradation products in posaconazole injection by LC-​TOF​/MS, LC-​MS​/MS and NMR
By Yang, Yidi; Zhu, Xi; Zhang, Fei; Li, Wei; Wu, Ying; Ding, Li
From Journal of Pharmaceutical and Biomedical Analysis (2016), 125, 165-177
Stability indicating HPLC method for the quantification of posaconazole and its related substances
By Govind, Sampath Kumar Reddy; Nagaraju, Ch. V. S.; Rajan, S. T.; Eshwaraiah, S.; Kishore, M.; Rakesh, M.; Chakravarthy, I. E.
From Pharma Chemica (2014), 6(1), 486-494, 9 pp..