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Posaconazole Impurity 15

SZ CAT No SZ-P022035
CAS No 2423024-27-3
Mol.F. C20H18ClF2N3O4S 
Mol.Wt. 469.9
Inv. Status Custom Synthesis


Chemical Name: ((3R,5S)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl 4-chlorobenzenesulfonate

Smiles: FC1=CC(F)=C([C@]2(CN3C=NC=N3)C[C@@H](COS(=O)(C4=CC=C(Cl)C=C4)=O)CO2)C=C1

Inchi: InChI=1S/C36H40F2N8O5/c1-3-34(25(2)48)46-35(49)45(23-42-46)30-7-5-28(6-8-30)40-14-15-43(24-47)29-9-11-31(12-10-29)50-18-26-17-36(51-19-26,20-44-22-39-21-41-44)32-13-4-27(37)16-33(32)38/h4-13,16,21-26,34,40,48H,3,14-15,17-20H2,1-2H3/t25-,26-,34+,36+/m0/s1

Influence of cyclodextrin on posaconazole stability, release and activity: Improve the utility of the drug
By Santana, Ana Cristina Sousa Gramoza Vilarinho; Nadvorny, Daniela; da Rocha Passos, Taisa Daiany; de La Roca Soares, Monica Felts; Soares-Sobrinho, Jose Lamartine
From Journal of Drug Delivery Science and Technology (2019), 53, 101153
 
Stability-​indicating HPLC method development and structural elucidation of novel degradation products in posaconazole injection by LC-​TOF​/MS, LC-​MS​/MS and NMR
By Yang, Yidi; Zhu, Xi; Zhang, Fei; Li, Wei; Wu, Ying; Ding, Li
From Journal of Pharmaceutical and Biomedical Analysis (2016), 125, 165-177
 
Stability indicating HPLC method for the quantification of posaconazole and its related substances
By Govind, Sampath Kumar Reddy; Nagaraju, Ch. V. S.; Rajan, S. T.; Eshwaraiah, S.; Kishore, M.; Rakesh, M.; Chakravarthy, I. E.
From Pharma Chemica (2014), 6(1), 486-494, 9 pp..