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Posaconazole Diastereoisomer 9 (S,S,S,S)

SZ CAT No SZ-P022073
CAS No NA
Mol.F. C37H42F2N8O4
Mol.Wt. 700.8
Inv. Status In Stock


Chemical Name: 4-(4-(4-(4-(((3S,5S)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-((2S,3S)-2-hydroxypentan-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one

Smiles: O=C1N([C@@H](CC)[C@@H](O)C)N=CN1C2=CC=C(N3CCN(C4=CC=C(OC[C@H]5CO[C@@](C6=CC=C(F)C=C6F)(CN7N=CN=C7)C5)C=C4)CC3)C=C2

Inchi: InChI=1S/C47H52N8O5/c1-3-45(35(2)59-33-36-7-5-4-6-8-36)55-47(58)54(34-48-55)42-15-13-39(14-16-42)51-27-31-53(32-28-51)41-19-23-44(24-20-41)60-46(57)49-37-9-11-38(12-10-37)50-25-29-52(30-26-50)40-17-21-43(56)22-18-40/h4-24,34-35,45,56H,3,25-33H2,1-2H3,(H,49,57)/t35-,45+/m0/s1

Influence of cyclodextrin on posaconazole stability, release and activity: Improve the utility of the drug
By Santana, Ana Cristina Sousa Gramoza Vilarinho; Nadvorny, Daniela; da Rocha Passos, Taisa Daiany; de La Roca Soares, Monica Felts; Soares-Sobrinho, Jose Lamartine
From Journal of Drug Delivery Science and Technology (2019), 53, 101153
 
Stability-​indicating HPLC method development and structural elucidation of novel degradation products in posaconazole injection by LC-​TOF​/MS, LC-​MS​/MS and NMR
By Yang, Yidi; Zhu, Xi; Zhang, Fei; Li, Wei; Wu, Ying; Ding, Li
From Journal of Pharmaceutical and Biomedical Analysis (2016), 125, 165-177
 
Stability indicating HPLC method for the quantification of posaconazole and its related substances
By Govind, Sampath Kumar Reddy; Nagaraju, Ch. V. S.; Rajan, S. T.; Eshwaraiah, S.; Kishore, M.; Rakesh, M.; Chakravarthy, I. E.
From Pharma Chemica (2014), 6(1), 486-494, 9 pp..