All Categories
  • All Categories
  • Accessories
  • Accessories & More
  • Butters & Eggs
  • Camera & Video
  • Mornitors
  • Tablets
  • Laptops
  • Handbags
  • Headphone & Speaker
  • Herbs & botanicals
  • Vegetables
  • Shop
  • Laptops & Desktops
  • Watchs
  • Electronic

Posaconazole Diastereoisomer 3 (S,R,R,R)

SZ CAT No SZ-P022010
CAS No 1229428-89-0
Mol.F. C37H42F2N8O4
Mol.Wt. 700.8
Inv. Status Under Synthesis


Chemical Name: 4-(4-(4-(4-(((3R,5S)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-((2R,3R)-2-hydroxypentan-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one

Smiles: FC1=C(C=CC(F)=C1)[C@@]2(C[C@H](COC3=CC=C(N4CCN(C5=CC=C(N(C=NN6[C@H](CC)[C@H](O)C)C6=O)C=C5)CC4)C=C3)CO2)CN7C=NC=N7

Inchi: InChI=1S/C37H42F2N8O4/c1-3-35(26(2)48)47-36(49)46(25-42-47)31-7-5-29(6-8-31)43-14-16-44(17-15-43)30-9-11-32(12-10-30)50-20-27-19-37(51-21-27,22-45-24-40-23-41-45)33-13-4-28(38)18-34(33)39/h4-13,18,23-27,35,48H,3,14-17,19-22H2,1-2H3/t26-,27+,35-,37+/m1/s1

Influence of cyclodextrin on posaconazole stability, release and activity: Improve the utility of the drug
By Santana, Ana Cristina Sousa Gramoza Vilarinho; Nadvorny, Daniela; da Rocha Passos, Taisa Daiany; de La Roca Soares, Monica Felts; Soares-Sobrinho, Jose Lamartine
From Journal of Drug Delivery Science and Technology (2019), 53, 101153
 
Stability-​indicating HPLC method development and structural elucidation of novel degradation products in posaconazole injection by LC-​TOF​/MS, LC-​MS​/MS and NMR
By Yang, Yidi; Zhu, Xi; Zhang, Fei; Li, Wei; Wu, Ying; Ding, Li
From Journal of Pharmaceutical and Biomedical Analysis (2016), 125, 165-177
 
Stability indicating HPLC method for the quantification of posaconazole and its related substances
By Govind, Sampath Kumar Reddy; Nagaraju, Ch. V. S.; Rajan, S. T.; Eshwaraiah, S.; Kishore, M.; Rakesh, M.; Chakravarthy, I. E.
From Pharma Chemica (2014), 6(1), 486-494, 9 pp..